Alarming Trends in Breast Cancer Mortality Rates Across Age Groups

Mar 6, 2025 at 11:05 AM

A recent study published in the Journal of Breast Imaging reveals concerning trends in breast cancer mortality rates. For women over 74 and under 40, the decline in mortality rates has halted. This stagnation is particularly alarming for older women, as it represents a new development. Researchers attribute this shift to increasing diagnoses of advanced-stage breast cancer, which carries a poor prognosis. The findings highlight the need for reassessment of current healthcare protocols and screening guidelines.

The research underscores the importance of addressing disparities in breast cancer outcomes across different age groups and ethnicities. While mortality rates have continued to decrease for Black women across all age groups, White women over 74 and under 40 have seen no further improvement. Additionally, Hispanic, Asian, and Native American women have also experienced stalled progress in mortality rate reductions. These insights suggest that tailored approaches may be necessary to combat these trends effectively.

Concerning Stagnation in Older Women's Breast Cancer Mortality Rates

For women aged 75 and above, a significant trend has emerged where the once steady decline in breast cancer mortality rates has come to a halt. This change marks a critical turning point, especially considering the historical context of declining rates since 1990. The cessation of this positive trend raises concerns about the effectiveness of current health strategies for this demographic.

The researchers found that from 1993 to 2013, breast cancer mortality rates among women 75 years and older decreased by 1.26% annually. However, this downward trajectory ceased after 2013. The study suggests that one of the primary reasons for this stagnation is the increase in stage IV breast cancer diagnoses within this age group. Stage IV, or metastatic, breast cancer has an extremely poor prognosis, with only a 31% five-year survival rate. This finding highlights the urgent need to reassess screening practices for older women, as some U.S. guidelines currently discourage mammograms for those over 74. Enhanced early detection methods could potentially reverse this troubling trend and save lives.

Stalled Progress in Younger Women's Breast Cancer Mortality Rates

Another significant concern arises from the stagnation in breast cancer mortality rates for women under 40. Previously, these rates had been steadily decreasing, but since 2010, they have remained flat. This development is particularly worrying, as it indicates a potential gap in current healthcare protocols for younger women. The research points to a rise in late-stage diagnoses as a key factor contributing to this stagnation.

From 1990 to 2010, breast cancer mortality rates for women aged 20 to 39 decreased by 2.79% annually. However, this positive trend has not continued into the more recent period. The study attributes this shift to a notable increase in stage IV breast cancer diagnoses among younger women, especially White women under 40. Furthermore, unfavorable trends have also been observed in Hispanic women aged 20-39. The authors emphasize that while breast cancer assessments are recommended for all women by age 25, screening is only advised for those under 40 who are at higher-than-average risk. This discrepancy suggests that current guidelines may need revision to better protect younger women. Additionally, the disparity in mortality rates between Black and White women under 40 highlights the need for alternative strategies to address the unique challenges faced by younger Black women in breast cancer prevention and treatment.